Curriculum of Gynecology
TOPIC 83
CHORIOCARCINOMA
RATIONALE
Gestational trophoblastic disease (GTD) includes a spectrum of interrelated tumors, including complete and partial mole, placental site trophoblastic tumor, and choriocarcinoma. GTD is among the rare human tumors that can be cured even in the presence of widespread dissemination. Advances in the pathogenesis, natural history, and treatment of GTD and current approach to management have to be understood.
GOALS
l Recognize the classification and the pathology of GTD
l Understand the prognostic factors and the diagnostic work-up of choriocarcinoma
l Recognize the protocols of both the treatment and followup of choriocarcinoma
LEARNING OBJECTIVES
By the end of this course, the student will be able to:
l State correctly the definition of choriocarcinoma
l Describe the pathology of choriocarcinoma
l Enumerate the prognostic factors of choriocarcinoma
l Describe symptoms and signs
l List and interpret different investigations
l Describe the lines of treatment
l State the protocol of followup
l Diagnose pathological changes in pathology jars
CONTENT
l Classification of GTD
l Pathology of choriocarcinoma
l Clinical picture and staging
l Diagnostic evaluation
l Prognostic scoring system
l Lines of treatment
l Protocol of followup
